A newly emerging COVID-19 variant, informally nicknamed the ‘Frankenstein’ strain, is grabbing the attention of health experts worldwide due to its unusual and painful symptom—an excruciating sore throat that many patients say is unlike anything they’ve experienced before.
Medical professionals report that this intense throat pain often appears early in the infection, sometimes even before a fever or cough, and can be so severe that it interferes with eating, drinking, or speaking.

This variant is believed to be a recombinant of multiple Omicron sub-variants, combining traits that allow it to spread more quickly and possibly dodge parts of the immune response—even in people who are vaccinated or have recovered from earlier infections.
Though it hasn’t been officially classified as a Variant of Concern by global health bodies, early patterns suggest that this strain could lead to a sharp rise in infections due to its high transmissibility.
What Makes This Variant Different?
Unlike previous strains where symptoms often started with mild fatigue or congestion, this variant is hitting the throat hard. Physicians in multiple countries have highlighted that this isn’t a typical sore throat—it’s sharp, persistent, and often severe.
Additional symptoms being reported include:
- Fever and chills
- Nasal congestion
- Body aches
- Fatigue
- Occasional loss of taste or smell
Where Has It Spread?
The ‘Frankenstein’ strain has been identified in parts of the UK, US, Japan, and India, with cases likely underreported due to the global decline in COVID testing. Some local health departments have already issued renewed masking advisories, particularly in crowded public settings and healthcare spaces.
Public Health Guidance
Doctors are advising people to watch for the early onset of sharp throat pain, isolate if symptoms develop, and test promptly. Vaccination—including booster doses—is still encouraged as a layer of protection, especially for vulnerable groups.
While there’s no evidence yet that this variant causes more severe illness overall, the rapid spread and intense symptoms could lead to increased strain on local health systems.
The emergence of the ‘Frankenstein’ strain serves as a reminder that COVID-19 continues to evolve. Health experts are calling for vigilance, early symptom recognition, and a cautious approach as more is learned about this new variant.